Shear Stress Triggers Angiogenesis of Late Endothelial Progenitor Cells via the PTEN/Akt/GTPCH/BH4 Pathway

Figure 1

The effect of different levels of LSS on in vitro function of late EPCs. (a) Quantification analysis of VEGF-induced migration of late EPCs ( vs. EPCs under static condition group, per group). (b) Quantification analysis of proliferative activity of late EPCs ( vs. EPCs under static condition group, per group). (c) Quantification analysis and representative photograph tube information of late EPCs (represented as relative value to EPCs under static condition group, vs. EPCs under static condition group, per group). Scale bar 200 μm. Least significant difference was applied for the post hoc test in statistical analysis. hpf = high power field.

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