Research Article
c-Jun Overexpression Accelerates Wound Healing in Diabetic Rats by Human Umbilical Cord-Derived Mesenchymal Stem Cells
Figure 1
In vitro aged hUC-MSCs exhibit reduced proliferative and migratory capacities along with decreased c-Jun expression. (a) The proliferative capacity of hUC-MSCs at passages 5, 10, and 15 determined with the CCK-8 assay. (b) The migratory capacity of hUC-MSCs at passages 5 and 15 evaluated with the in vitro scratch assay. (c, d) The relative c-Jun mRNA (c) and protein (d) levels in hUC-MSCs at passages 5, 10, and 15 by qRT-PCR and western blot analysis, respectively. , , , , .
(a) |
(b) |
(c) |
(d) |