Concise Review: The Regulatory Mechanism of Lysine Acetylation in Mesenchymal Stem Cell Differentiation

Table 1

The classification of KATs/KDACs.

Enzyme	Family		Abbreviations	Subcellular localization
KATs	GCN5		GCN5 (KAT2A), PCAF (KAT2B)	Nucleus
	P300		CBP (KAT3A), P300 (KAT3B)	Nucleus
	MYST		Tip60 (KAT5), MOZ (KAT6A); MORF (KAT6B), HBO1 (KAT7), MOF (KAT8)	Nucleus
	Other		ESCO1, ESCO2, HAT1	Nucleus
			TAT1	Cytoplasm
KDACs	Class I		HDAC1, HDAC2, HDAC3, HDAC8	Nucleus
	Class II	Class IIa	HDAC4, HDAC5, HDAC7, HDAC9	Nucleus
		Class IIb	HDAC6, HDAC10	Cytoplasm
	Class IV		HDAC11	Nucleus
	Class III (SIRT)		SIRT1, SIRT6	Nucleus
			SIRT2	Cytoplasm
			SIRT3, SIRT4, SIRT5	Mitochondria
			SIRT7	Nucleolus