Phosphodiesterase 10A Is a Mediator of Osteogenic Differentiation and Mechanotransduction in Bone Marrow-Derived Mesenchymal Stromal Cells

<div>Effect of papaverine on viability and apoptosis of hMSCs derived from four donors. Cells were treated with 0, 1, 10, and 100 <i>μM</i> papaverine, and viability (a) and apoptosis assays (b) were performed 24, 48, and 72 h later. Relative luminescence is given. 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Each measurement was performed in technical triplicate. 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Stem Cells International

fig3

Figure 3

Figure 3: Phosphodiesterase 10A Is a Mediator of Osteogenic Differentiation and Mechanotransduction in Bone Marrow-Derived Mesenchymal Stromal Cells 