Aging Induced p53/p21 in Genioglossus Muscle Stem Cells and Enhanced Upper Airway Injury

<div>The proliferation and migration of GG MuSCs declined with aging. (a) Primary cells were obtained from GG muscle fibers, and cells showed a spindle morphology. (b) GG MuSC markers Pax7 and MyoD were positive in cells. (c) Wound healing of GG MuSCs derived from four age groups. (d) The migration of GG MuSCs derived from four age groups. (e) The wound healing and migration rate are significantly lower in 12-month-old compared to other age groups at 24 h. 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Stem Cells International

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Figure 3

Figure 3: Aging Induced p53/p21 in Genioglossus Muscle Stem Cells and Enhanced Upper Airway Injury 