Research Article

Spinal Reflex Recovery after Dorsal Rhizotomy and Repair with Platelet-Rich Plasma (PRP) Gel Combined with Bioengineered Human Embryonic Stem Cells (hESCs)

Figure 5

Representative immunofluorescence micrographs of GFAP (astrocytes) and Iba-1 (microglia) immunolabeling on the ipsilateral side of the spinal dorsal superficial laminae after lesion rhizotomy and repair. A significant increase in glial reactivity was observed after lesion induction. However, neither human PRP gel application nor hESC engrafting exacerbated glial reactivity, in comparison to the DRZ group. These findings directly reflected in the functional recovery from these groups. .