In Vitro Oxygen-Glucose Deprivation-Induced Stroke Models with Human Neuroblastoma Cell- and Induced Pluripotent Stem Cell-Derived Neurons

Figure 4

Apoptosis of SH-SY5Y- and hiPSC-neurons after OGD and ASC coculture, as determined by cleaved caspase-3 (cl-Casp3) staining. Representative images of cl-Casp3 staining after 72 h of reperfusion in SH-SY5Y-neurons (/group/experiment, representative image of two to four separate experiments; two to four images were taken of each well) and hiPSC-neurons (/group/experiment, representative images of two separate experiments; 4 images were taken of each well). Blue = nuclei; green = cl-Casp3. Scale bar, 50 μm.