Quantification and Comprehensive Analysis of Mesenchymal Stromal Cells in Bone Marrow Samples from Sickle Cell Disease Patients with Osteonecrosis

Figure 2

Quantification of CD271⁺CD45^-/low cells in BMA and BM-MNC. Counting of CD271⁺CD45^-/low cells in (a) BMA and (b) BM-MNC from SCD and NS patients. Data are reported as the median and interquartile range. (c) The fold increase of CD271⁺CD45^low cell counts after sample processing in SCD and NS. Wilcoxon matched-pairs signed-rank test. (d) Correlation between the frequency of CFU-F and CD271⁺CD45^-/low cell counts. A Spearman test was used for the correlation analysis; black and dashed lines across data sets indicate of best fit for each group. ; ; .

(a)

(b)

(c)

(d)