Quantification and Comprehensive Analysis of Mesenchymal Stromal Cells in Bone Marrow Samples from Sickle Cell Disease Patients with Osteonecrosis

Table 1

Distribution of cell number, progenitor cell populations, and frequency of CFU-F with BM processing.

	BMA			BM-MNC
	SCD	NS		SCD	NS
()^§			<0.01			<0.001
CFU-F/mL	110 (34-278)	15 (10-45)	<0.01	216 (72-553)	46 (21-66)	<0.001
	7.8 (3.4–14.4)	6.7 (2.9–11.0)	>0.05	66.7 (14.2–260)		<0.05
	155 (120.5-189.5)	126 (94-173)	>0.05	485.3 (53.4 -1479)	435.1 (105-3763)	>0.05

Demographic and baseline biochemical characteristics of patients. Variables presented as median (interquartile range). ^§Except where noted otherwise. Abbreviations: BMA: bone marrow aspirate; BM-MNCs: bone marrow mononuclear cells; CFU-Fs: colony-forming unit fibroblasts.