Research Article

Generation of Insulin-Producing Cells from Canine Adipose Tissue-Derived Mesenchymal Stem Cells

Figure 2

Expression of endocrine pancreatic marker genes in undifferentiated and differentiated adipose tissue-derived mesenchymal stem cells. Pdx-1, Ngn3, and GLUT2 mRNA expressions in insulin-producing cells (IPC) generated under the three-dimensional culture system with μ-pieces were 4.1, 5.2, and 4.3 times higher, respectively, than those in undifferentiated adipose tissue-derived mesenchymal stem cells (AT-MSCs). Data are expressed as the . vs. AT-MSC.