Research Article

Vessel Wall-Derived Mesenchymal Stromal Cells Share Similar Differentiation Potential and Immunomodulatory Properties with Bone Marrow-Derived Stromal Cells

Figure 1

Comparison of morphology and multilineage differentiation potential of vessel wall- and bone marrow-derived MSCs. (a) After passage 5, the isolated MSC populations derived from bone marrow (BM) or SV and human umbilical cord vein (HUVEC) exhibited spindle-shaped morphology. (b) BM- and SV-derived MSCs exhibited the capability to differentiate into the three canonical differentiation pathways, such as fat, bone, and cartilage. (c) Cytoskeletal actin labeled by phalloidin-TRITC, vimentin, and iNOS by rabbit monoclonal antibody, visualized by anti-rabbit conjugated with NorthernLights493. Nuclei stained with Hoechst. Original magnification: ×200. Data is representative of four experiments.
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