Research Article

Vessel Wall-Derived Mesenchymal Stromal Cells Share Similar Differentiation Potential and Immunomodulatory Properties with Bone Marrow-Derived Stromal Cells

Table 1

Detailed phenotypic analysis of BM-MSCs and SV-MSCs.

BM-MSCSV-MSCHUVEC

Percentage of positive cells (%)
Hematopoietic markersCD14
CD34
CD36
CD45
CD47
CD69
CD133
CD117
CXCR4
HLA-DR

Endothelial markersCD31
CD144
VEGFR2/KDR
CD104/integrin β4

MSC/fibroblast markersCD73
CD90/Thy-1
CD105/endoglin
CD147/neurothelin
PDGF Rβ

Cell adhesion moleculesCD29/integrin β1
CD44/H-CAM
CD49a
CD49b
CD49f
CD54/ICAM
CD56/NCAM
CD146/MCAM
CD166/ALCAM

Expression of surface markers related to different cell types was measured by flow cytometry. The percentage of positive cells in SV-MSC culture was compared to that of BM-MSCs as well as HUVECs, as vein endothelial control. (Data are presented as ; for SV-MSC, for BM-MSC, for HUVEC. , , vs. SV-MSCs determined by Student -test).