Research Article

Hypoxia-Preconditioned Wharton’s Jelly-Derived Mesenchymal Stem Cells Mitigate Stress-Induced Apoptosis and Ameliorate Human Islet Survival and Function in Direct Contact Coculture System

Figure 8

p53 protein level in human islets cocultured with Hpc-MSCs and Nc-MSCs. (a) p53 protein immunocytochemistry. (b) p53 protein level in the islets as graphs based on the H-score method. A comparison was done between the control and each cocultured islets (yellow arrows show positive protein expression). Scale bar: 10 μm. , , and . Nc-MSCs: normoxia condition mesenchymal stem cells; Hpc-MSCs: hypoxia preconditioning MSCs; D: direct coculture; I: indirect coculture.
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