Combined Transplantation of Mesenchymal Stem Cells and Endothelial Colony-Forming Cells Accelerates Refractory Diabetic Foot Ulcer Healing

Figure 1

Photographs of treated ulcer (right foot) and control ulcer (left foot) over time with depiction of wound surface area of patient #1 (a). Patient #1 had two wounds in both foots; the right foot was injected cells and the left foot as control. The healing rate of the wound injected cells was obviously faster than control wounds. Photographs of treated ulcer (the first and third toes) and control ulcer (the other two toes) over time with depiction of wound surface area of patient #2 (b). Patient #2 had four wounds in his left foot; the first and third toes were injected cells (red arrow) and the other two toes as control. The healing rate of the toes injected cells was obviously faster than control wounds. Photographs of treated ulcer (the fifth toe) and control ulcer (the other two toes) over time with depiction of wound surface area of patient #3 (c). Patient #3 had three wounds in his left foot; the fifth toe was injected cells (red arrow) and the other two toes as control. The wound was covered with white epithelium at the fourth day after cell treatment. The healing rate of the fifth toe was obviously faster than control wounds.

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