Research Article
Medications for Hypertension Change the Secretome Profile from Marrow Stromal Cells and Peripheral Blood Monocytes
Figure 5
Losartan reduces the cytokine secretions of IL-1β, IL-8, MCP-1, TNF-α, IL-1RA, IL-6, and VEGF from cocultures of healthy control monocytes with MSCs after 24 hours of exposure, while decreasing only IL-8 secretions from cocultures involving stoke patient-derived monocytes without changing any other cytokine secretions. Significance is shown by . All fold changes are as compared to vehicle control.
(a) |
(b) |
(c) |
(d) |
(e) |
(f) |
(g) |
(h) |