Transplantation Site Affects the Outcomes of Adipose-Derived Stem Cell-Based Therapy for Retinal Degeneration

Figure 2

Protective effects of rASCs on retina in SI-induced rat RDD model. rASCs were transplanted into the vitreous chamber. (a) Representative ERG waveforms recorded at different time points (the calibration indicates 100 μV vertically and 25 ms horizontally). (b) Quantitative analysis of ERG b-wave amplitude (). (c) Representative DAPI-stained micrographs of retinal samples (). (d) Representative micrographs of retinal cryosections stained with TUNEL (). (e) Statistical analysis of the percentage of the apoptotic cells in GCL, INL, and ONL (). Results are expressed as ; compared with the rASC group. GCL: ganglion cell layer; INL: inner nuclear layer; ONL: outer nuclear layer.

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