|
Cell source | Wound type | Function | Reference |
|
LPS-pretreated hUC-MSCs | Diabetic cutaneous wound | Suppress inflammation and promote healing of diabetic wounds | [63] |
H2O2-pretreated ADSCs | Skin flap model: ligation of blood vessels and blood perfusion | Improve the survival rate of animals with skin flaps; promote neovascularization and inhibit inflammation and cell apoptosis | [70] |
Salidroside-pretreated mouse MSCs | Diabetic wound | Accelerate reepithelialization and wound closure | [71] |
Pioglitazone-pretreated BMSCs | Diabetic wound | Promote angiogenesis and enhance wound repair | [72] |
Neonatal serum-pretreated BMSCs | Skin wound healing model | Promote angiogenesis | [73] |
Melatonin-pretreated hBMSCs | Rat diabetic wound healing model | Immunosuppressive effects | [38] |
hUC-MSCs | Scratch assay and human skin permeation | Accelerate collagen synthesis and cell migration | [74] |
hUC-MSCs | Rat burn injury model | Enhance wound closure and inhibit skin cell apoptosis | [2] |
hUC-MSCs | Severe burn | Suppress inflammation and promote neovascularization | [75] |
hUC-MSCs | Rat model of deep second-degree burn injury | Accelerate angiogenesis | [76] |
hiPSCs | UV irradiation damage of human dermal fibroblasts | Ameliorate aging of skin fibroblasts | [77] |
hiPSC-MSCs | Rat skin wound model | Promote collagen synthesis and enhance angiogenesis | [50] |
Menstrual blood-derived MSCs | Diabetic foot ulcer | Suppress inflammation and accelerate wound healing | [78] |
Human fibrocytes | Genetically diabetic ulcers | Enhance angiogenesis and augment keratinocyte proliferation and migration | [46] |
Platelet-rich plasma | Rat diabetic wound model | Promote reepithelialization | [79] |
Platelets | Ischemic wound healing | Regulate collagen synthesis and restore dermal architecture | [80] |
Human dermal fibroblasts | UVB-induced skin photoaging | Reduce skin photoaging and inflammation | [81] |
Human endothelial progenitor cells | Rat diabetic wound model | Regulate endothelial function | [82] |
Human urine-derived stem cells | Mouse diabetic wound model | Promote the angiogenic activities of endothelial cells | [44] |
Macrophage-derived Exos | Diabetic wound model | Promote endothelial cell proliferation, angiogenesis, and reepithelialization | [83] |
Human amniotic epithelial cells | Rat full-thickness skin wound model | Stimulate fibroblast proliferation and migration; decrease scar formation | [55] |
Oral mucosal epithelial cells | Rat full-thickness skin wound model | Proregenerative effects | [84] |
|