Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote the Proliferation of Schwann Cells by Regulating the PI3K/AKT Signaling Pathway via Transferring miR-21

<div>hUCMSC-EVs promoted the proliferation of Schwann cells <i>in vivo</i>. (a) Representative picture showing the macroscopic appearance of regenerated nerve in nerve conduit after sciatic nerve transection at 57 days. (b, c) S100 immunofluorescence staining (green) and statistical analysis of S100 intensity, scale bar: 100 <i>μ</i>m. (d, e) BrdU immunofluorescence staining (red) and statistical analysis of BrdU intensity, scale bar: 100 <i>μ</i>m. 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Stem Cells International

fig2

Figure 2

Figure 2: Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote the Proliferation of Schwann Cells by Regulating the PI3K/AKT Signaling Pathway via Transferring miR-21 

Figure 2 | Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote the Proliferation of Schwann Cells by Regulating the PI3K/AKT Signaling Pathway via Transferring miR-21 