Review Article
The Clinical Trials of Mesenchymal Stromal Cells Therapy
Table 2
Active clinical trials on mesenchymal stromal/stem cell-based therapy started during 2016-2020 (U. S. National Library of Medicine).
| Organ system | Disease/syndrome | Phase | Date | Country | Source | Transplantation | CT code |
| Cardiovascular | Hypoplastic left heart syndrome | 1 and 2 | 2018 | United States | Bone marrow | Allotransplant | NCT03525418 | Gastrointestinal | Cystic fibrosis | 1 | 2016 | United States | Bone marrow | Allotransplant | NCT02866721 | Gastrointestinal | Diabetes | 1 and 2 | 2017 | United States | ND | Allotransplant | NCT02886884 | Gastrointestinal | Inflammatory bowel | 1 and 2 | 2017 | Jordan | Wharton’s jelly | Allotransplant | NCT03299413 | Gastrointestinal | Primary sclerosing cholangitis | 1 and 2 | 2017 | China | Umbilical cord | Allotransplant | NCT03516006 | Gastrointestinal | Xerostomia | 1 | 2019 | Denmark | Adipose tissue | Allotransplant | NCT03874572 | Immune | Graft versus host disease | 1 and 2 | 2016 | Spain | Adipose tissue | Autotransplant | NCT02687646 | Immune | Graft versus host disease | 1 | 2018 | United States | Umbilical cord Wharton’s jelly | Allotransplant | NCT03158896 | Integumentary | Epidermolysis bullosa | 1 and 2 | 2018 | Spain | Bone marrow | Allotransplant | NCT04153630 | Integumentary | Epidermolysis bullosa | 1 and 2 | 2019 | United Kingdom | Skin | Allotransplant | NCT03529877 | Integumentary | Inflammation | 1 and 2 | 2018 | United States | Bone marrow | Allotransplant | NCT03059355 | Integumentary | Psoriasis | 1 and 2 | 2017 | China | Adipose tissue | Allotransplant | NCT03265613 | Nervous | Alcoholism | 1 and 2 | 2018 | United States | ND | Allotransplant | NCT03265808 | Nervous | Alzheimer’s disease | 1 and 2 | 2020 | United States | Adipose tissue | Autotransplant | NCT04228666 | Nervous | Alzheimer’s disease | 1 | 2016 | United States | Bone marrow | Allotransplant | NCT02600130 | Nervous | Amyotrophic lateral sclerosis | 3 | 2017 | United States | Umbilical cord | Allotransplant | NCT03280056 | Nervous | Cerebral palsy | 1 and 2 | 2016 | Jordan | Bone marrow | Autotransplant | NCT03078621 | Nervous | Cerebral palsy | 2 | 2017 | Iran | Umbilical cord | Allotransplant | NCT03795974 | Nervous | Cerebral palsy | 1 and 2 | 2018 | United States | Umbilical cord | Allotransplant | NCT03473301 | Nervous | Huntington disease | 2 | 2018 | Brazil | Dental pulp | Allotransplant | NCT03252535 | Nervous | Huntington disease | 1 | 2017 | Brazil | Dental pulp | Allotransplant | NCT02728115 | Nervous | Multiple sclerosis | 2 | 2018 | United States | Bone marrow | Autotransplant | NCT03355365 | Nervous | Multiple sclerosis | 2 | 2019 | United States | ND | Autotransplant | NCT03799718 | Nervous | Multiple system atrophy | 1 | 2018 | Korea | Bone marrow | Autotransplant | NCT04495582 | Nervous | Nervous injury | 1 and 2 | 2017 | China | Umbilical cord | Allotransplant | NCT03291366 | Nervous | Parkinson’s disease | 2 | 2017 | Belarus | Bone marrow | Autotransplant | NCT04146519 | Nervous | Spinal cord injury | 1 | 2017 | United States | Adipose tissue | Autotransplant | NCT03308565 | Respiratory | COVID-19 | 1 and 2 | 2020 | Spain | Adipose tissue | Allotransplant | NCT04366323 | Respiratory | COVID-19 | 2 | 2020 | United States | Adipose tissue | Allotransplant | NCT04362189 | Respiratory | COVID-19 | 2 | 2020 | United States | Adipose tissue | Autotransplant | NCT04349631 | Respiratory | COVID-19 | 1 and 2 | 2020 | France | Umbilical cord Wharton’s jelly | Allotransplant | NCT04333368 | Skeletal | Knee osteoarthritis | 1 | 2019 | United States | Adipose tissue | Autotransplant | NCT04043819 | Skeletal | Lateral epicondylitis | 2 | 2018 | Korea | Adipose tissue | Allotransplant | NCT03449082 | Skeletal | Osteoarthritis | 2 | 2017 | Korea | Adipose tissue | Autotransplant | NCT03509025 | Skeletal | Osteoarthritis | 3 | 2019 | Korea | Adipose tissue | Autotransplant | NCT03990805 | Skeletal | Osteoarthritis | 1 | 2016 | Jordan | Bone marrow | Autotransplant | NCT03067870 | Urinary | Fistula | 1 | 2017 | United States | Adipose tissue | Autotransplant | NCT02808208 | Urinary | Kidney injury | 1 and 2 | 2017 | United States | Bone marrow | Allotransplant | NCT03015623 | Urinary | Nephrosis | 2 | 2016 | China | Bone marrow | Autotransplant | NCT02966717 |
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ND: no data.
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