Research Article

Human Umbilical Mesenchymal Stromal Cells Mixed with Hyaluronan Transplantation Decreased Cartilage Destruction in a Rabbit Osteoarthritis Model

Figure 3

qRT-PCR and immunohistochemistry (IHC) of HUCMSCs after chondrogenic differentiation. (a) Expression of chondrogenic genes (SOX9, aggrecan, and type II collagen) in HUCMSCs is treated with or without hyaluronic acid (HA) compared to no differentiation HUCMSCs. (b) The gross picture of the pellet differentiated from HUCMSCs is treated with or without HA. (c) H&E staining of the pellet and HUCMSC (negative control). (d) Safranin O staining of the pellet and HUCMSC (negative control). (e) IHC of aggrecan and type II collagen of the pellet and HUCMSC (negative control). (f) The quantification of aggrecan and type II collagen. . , , and . Ctrl: control.