Research Article

Proteogenomic Analysis Reveals Proteins Involved in the First Step of Adipogenesis in Human Adipose-Derived Stem Cells

Figure 3

Unseen genes in the transcriptome are revealed by proteomics. (a) Venn diagram comparing all proteins and total mRNAs identified in the CT (left Venn diagram) and ADI (right Venn diagram) conditions. (b) Venn diagrams comparing all proteins and polysomal mRNAs identified in the CT (left Venn diagram) and ADI (right Venn diagram) conditions. Boxes show hidden proteins detected exclusively in the CT (5 proteins) and ADI (4 proteins) conditions. (c) Protein-protein interaction network demonstrating the identified hidden proteins. CT represents undifferentiated hASC, ADI represents 24 h-differentiated cells, and BOTH represents total and polysomal fractions.
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