miR-20a Overexpression in Adipose-Derived Mesenchymal Stem Cells Promotes Therapeutic Efficacy in Murine Lupus Nephritis by Regulating Autophagy

<div>Effect of miR-20a-ADSC/ADSC treatment on the podocyte of different groups. (a–d) Transmission electron micrograph showing autophagosomes (arrows) in the podocytes from the normal control (a), lupus (b), ADSC (c), and miR-20a (d) groups (8,000x). (e) Number of autophagosomes per podocyte. (f) Nephrin and podocin mRNA relative expression levels. (g) Nephrin and podocin relative protein expression levels. (h) Western blot analysis of nephrin and podocin expression in different groups. 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Control: normal control group; lupus: lupus group; ADSC: adipose-derived stem cell group; miR-20a: miR-20a-ADSC group.</div>

Stem Cells International

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Figure 4

Figure 4: miR-20a Overexpression in Adipose-Derived Mesenchymal Stem Cells Promotes Therapeutic Efficacy in Murine Lupus Nephritis by Regulating Autophagy 

Figure 4 | miR-20a Overexpression in Adipose-Derived Mesenchymal Stem Cells Promotes Therapeutic Efficacy in Murine Lupus Nephritis by Regulating Autophagy 