miR-370-3p as a Novel Biomarker Promotes Breast Cancer Progression by Targeting FBLN5

Figure 3

miR-370-3p can promote migration and proliferation of breast cancer cells in vivo. (a–c) Observe the appearance, weight, and volume of breast tumor in nude mice subcutaneously formed by MDA-MB-231 cells transfected with MNC, 370-mimics, INC, and 370- inhibitor. , . (d) The expression of miR-370-3p in the breast tumor tissues formed by MDA-MB-231 cells transfected with MNC, 370-mimics, INC, and 370-inhibitors which were injected into subcutaneous of nude mice was detected by quantitative RT-PCR. , . (e) The expression of EMT-related proteins in control and miR-370-3p-overexpressing cells or miR-370-3p knockdown cells were examined by using western blot. , , .

(a)

(b)

(c)

(d)

(e)