Chemically Defined Conditions Mediate an Efficient Induction of Dental Pulp Pluripotent-Like Stem Cells into Hepatocyte-Like Cells

Figure 1

Molecular evaluation of different signaling factors and biomaterials on the generation of definitive endoderm lineage. qRT-PCR was performed for the indicated genes at day 5 of DPPSC differentiation into DE lineage. (a) Cells treated with differentiation conditional media supplemented with indicated signaling factors. (b) Cells were seeded on precoated plates with/without the described scaffolds or cocultured with HepG2 cells. Results were normalized to GAPDH and expressed relative to undifferentiated cells at day. Data are shown as the (). .

(a)

(b)