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Cell type | Cell application form | Tissue regeneration | Reference |
|
PDLSCs | PDLSC stem cell assistance in periodontal regeneration technique (SAI-PRT) | Periodontal tissue | [79, 80] |
Autologous PDLSCs, PDLSC pellets, and cell sheet fragment | Periodontal tissue | (ClinicalTrials.gov identifier: NCT01357785, NCT01082822) |
|
DPSCs | DPSC rejection medicine | Alveolar bone (phase II clinical trial) | (cde.org.cn identifier: CXSL1700137) |
Autologous DPSC combined advanced therapy medicinal product (ATMP) | Dental pulp (early phase 1 clinical trial) | (ClinicalTrials.gov identifier: NCT02842515) |
Encapsulated DPSCs | Dental pulp | (ClinicalTrials.gov identifier: NCT03102879) |
Allogenic DPSCs | Osseointegration | (ClinicalTrials.gov identifier: NCT02731586) |
Leukocyte-platelet-rich fibrin (L-PRF) combined with DPSCs | Periodontal tissue | (ClinicalTrials.gov identifier: NCT04641533) |
Micrograft-enriched DPSCs | Periodontal tissue | (ClinicalTrials.gov identifier: NCT03386877) |
DPSC injection medicine | Bone tissue (osteoarthritis) (early phase 1 clinical study) | (ClinicalTrials.gov identifier: NCT04130100) |
|
SCAP | DPSCs+mineral trioxide aggregate (MTA)+platelet-rich fibrin (PRF) | Odontoblast and dentin | [137] |
|
SHED | Autologous SHED pellet | Dental pulp and periodontal tissue | (ClinicalTrials.gov identifier: NCT01814436) |
Autogenous human SHED associated with hydroxyapatite/collagen | Bone tissue (alveolar cleft) | (ClinicalTrials.gov identifier: NCT03766217) |
SHED injection | Liver tissue (Early phase 1 clinical trial) | (ClinicalTrials.gov identifier: NCT03957655) |
|
GMSCs | GMSCs from palate soft tissue | Periodontal tissue | (ClinicalTrials.gov identifier: NCT03570333) |
GMSCs and collagen scaffolds | Periodontal tissue (phase 1 and phase 2 clinical trial) | (ClinicalTrials.gov identifier: NCT03137979) |
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