Extracellular Vesicles Released from Neprilysin Gene-Modified Human Umbilical Cord-Derived Mesenchymal Stem Cell Enhance Therapeutic Effects in an Alzheimer’s Disease Animal Model

<div>Experimental schedule. Two weeks after A<i>β</i> injection into the bilateral hippocampus, stem cells were injected twice at intervals of 1 week. A week after last injection of stem cells, various behavior tests and immunohistochemical analyses were performed. EV study was performed on a day after first stem cell injection. A<i>β</i>: <i>β</i>-amyloid; MSC: mesenchymal stem cell; EV: extracellular vesicle.</div>

Stem Cells International

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Figure 1: Extracellular Vesicles Released from Neprilysin Gene-Modified Human Umbilical Cord-Derived Mesenchymal Stem Cell Enhance Therapeutic Effects in an Alzheimer’s Disease Animal Model 

Figure 1 | Extracellular Vesicles Released from Neprilysin Gene-Modified Human Umbilical Cord-Derived Mesenchymal Stem Cell Enhance Therapeutic Effects in an Alzheimer’s Disease Animal Model 