Regulatory Effect of Mesenchymal Stem Cells on T Cell Phenotypes in Autoimmune Diseases

Figure 2

MSCs relieve RA by regulating T cells. MSCs can regulate the balance of T cells by homing to the articular cavity and secreting a series of cytokines that increase the anti-inflammatory activity of the environment. T cells are also regulated via the transfer of mitochondria from MSCs to T cells. Additionally, MSCs under endoplasmic reticulum stress can also play a regulatory role in inducing T cells.