Review Article

Regulatory Effect of Mesenchymal Stem Cells on T Cell Phenotypes in Autoimmune Diseases

Table 1

The surface markers and differentiation potential of different kinds of MSCs.

SourcesSurface markerDifferentiation potentialReference

BM-MSCsCD271(+), CD59(+), CD81(+), CD47(+), CD151(+), CD147(+), CD98(+), CD143(-), Lin (-) CD45(-), CD140a (PDGFRα) (low/-)Strong adipogenic and osteogenic potential, poor chondrogenic potential, strong differentiation potential of corneal epithelial cells, and cardiac progenitors[1418]
UC-MSCsCD73(+), CD90(+), CD105(+), CD44(+), CDH-1(+), CD29(+), CD34(-), CD45(-)Muscle, neurogenic cells, hepatocyte-like cells, endothelial lineage[1923]
AD-MSCsCD45(-), HLA-DR(-), CD44(+), CD106(+), CD34(+), CD90(+), CD105(+)Strong adipogenic and osteogenic potential, poor chondrogenic potential, poor differentiation potential of corneal and muscle[14, 16, 17, 2426]
DP-MSCsTRO-1(+), CD146(+), CD29(+), CD90(+), CD105(+), CD44(+), CD59(+), CD73(+), CD146(-), CD34(-), CD45(-), CD11b(-), CD45(-)Osteogenic, adipogenic, chondrogenic, fibroblast lineage, neural stem cells[27, 28]
SD-MSCsCD9(+), CD10(+), CD13(+), CD44(+), CD54(+), CD55(+), CD90(+), CD105(+), CD166(+), D7-FIB(+), CD14(-), CD20(-), CD45(-), CD133(-)Strong chondrocyte, osteocyte, and adipocyte differentiation ability, as well as muscle differentiation[16, 29]