PRMT7: A Pivotal Arginine Methyltransferase in Stem Cells and Development

Figure 1

Biological functions of PRMT7 in mice and humans. PRMT7, a type III protein arginine methyltransferase, regulates the proliferation and differentiation of stem cells and promotes cancer metastasis. Deficiency of PRMT7 causes developmental defects in many systems. PRMT7: protein arginine methyltransferase 7; MMA: monomethyl arginine.