Long-Term Effects of Adjuvant Intravitreal Treatment with Autologous Bone Marrow-Derived Lineage-Negative Cells in Retinitis Pigmentosa

Table 3

Correlations between the BCDVA (ETDRS letters) and selected functional parameters in eyes treated with intravitreal injection of autologous Lin− cells.

	BCDVA (ETDRS letters)		BCNVA (Snellen)		Contrast sensitivity (number of letters on Pelli-Robson chart)
	Rs	value	Rs	value	Rs	value
Pretreatment	Ref.		−0.516	0.075	+0.427	0.033
1 month	+0.798	<0.001	−0.079	0.713	+0.563	0.003
3 months	+0.802	<0.001	−0.418	0.033	+0.379	0.056
6 months	+0.806	<0.001	−0.506	0.008	+0.537	0.005
9 months	+0.791	<0.001	−0.582	0.002	+0.514	0.007
12 months	+0.727	<0.001	−0.178	0.384	+0.407	0.048

Abbreviations: BCDVA: best corrected distance visual acuity; ETDRS: Early Treatment Diabetic Retinopathy Study; Lin− cells: lineage-negative cells; logMAR: Logarithm of the Minimum Angle of Resolution; BCNVA: best corrected near visual acuity; Rs: Spearman’s rank correlation coefficient. Spearman’s rank correlation coefficient for evaluation of correlation with pretreatment BCDVA value. Spearman’s rank correlation coefficient for evaluation of correlation with pretreatment BCDVA and presented parameters in corresponding time points.