Extracellular Vesicles: Novel Roles in Neurological Disorders

Figure 2

Roles of exosomes as intercellular communication mediators under physiological and pathological conditions. Under physiological or pathological conditions, cells can multidirectionally deliver substances and exchange information through exosomes. nGDF: nervous growth/differentiation factor; AEA: N-arachidonoylethanolamine; PLP: proteolipid protein; CNP: 23-cyclic-nucleotide-phosphodiesteras; PrP: prion protein; Aβ: amyloid β; IDE: insulin-degrading enzyme; SOD1: mutant superoxide dismutase.