Research Article

Pharmacological Preconditioning Improves the Viability and Proangiogenic Paracrine Function of Hydrogel-Encapsulated Mesenchymal Stromal Cells

Figure 3

Celastrol increases the viability of encapsulated MSC in low serum media: (a) metabolic activity, at days 2 and 4, of hMSC pretreated with 1 μM of celastrol or vehicle (DMSO 0.1% ), encapsulated in 200 μL of hydrogel, and incubated in low serum media; , , ( versus the vehicle at each time point); (b) live/dead pictures taken at day 4 (viable cells: green, dead cells: red; scale μm).
(a)
(b)