Nsd2 Represses Endogenous Retrovirus MERVL in Embryonic Stem Cells

Figure 3

Nsd2 overexpression rescues the expression of MERVL and 2-cell genes. (a) qPCR analysis of Nsd2 expression after overexpression of Nsd2 in Ssrp1^-/- ESC. The results were shown as , biologically independent replicates and normalized to Gapdh. (b) qPCR analysis of the expression of MERVL after overexpression of Nsd2 in Ssrp1^-/- ESC. , . (c) qPCR analysis of the expression of 2-cell marker genes Zscan4 and Dux after overexpression of Nsd2 in Ssrp1^-/- ESC. Ctrl: control; OE: overexpression; , ; ; .

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