Potency of Bone Marrow-Derived Mesenchymal Stem Cells and Indomethacin in Complete Freund’s Adjuvant-Induced Arthritic Rats: Roles of TNF-<i>α</i>, IL-10, iNOS, MMP-9, and TGF-<i>β</i>1

<div>Schematic diagram showing the immunomodulatory effect of BM-MSCs+IMC administered concurrently in CFA-induced arthritis. IMC: indomethacin; BM-MSCs: bone marrow-derived mesenchymal stem cells; Th2: T helper 2; DC: dendritic cell; IL-10: interleukin 10; T cell: T lymphocytes; B cell: B lymphocytes; Mono: monocytes; Neut: neutrophils; SM: synovial membrane; iNOS: inducible nitric oxide synthase; TGF-<i>β</i>1: transforming growth factor-beta-1; TNF-<i>α</i>: tumor necrosis factor-alpha; anti-CCP: anticyclic citrullinated peptide antibody; MMP-9: matrix metalloproteinase-9.</div>

Stem Cells International

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Figure 11

Figure 11: Potency of Bone Marrow-Derived Mesenchymal Stem Cells and Indomethacin in Complete Freund’s Adjuvant-Induced Arthritic Rats: Roles of TNF-<i>α</i>, IL-10, iNOS, MMP-9, and TGF-<i>β</i>1 

Figure 11 | Potency of Bone Marrow-Derived Mesenchymal Stem Cells and Indomethacin in Complete Freund’s Adjuvant-Induced Arthritic Rats: Roles of TNF-α, IL-10, iNOS, MMP-9, and TGF-β1 