Bone Mesenchymal Stem Cells Contribute to Ligament Regeneration and Graft–Bone Healing after Anterior Cruciate Ligament Reconstruction with Silk–Collagen Scaffold

<div>(a) The microstructure of silk fibers before degumming: the surface is coated with the glue-like protein sericin. (b) Under SEM, the surface of silk fibroins becomes smooth after complete degumming; the average diameter is about 10 <i>μ</i>m. (c) The microstructure of silk-collagen scaffold after the dehydrothermal crosslinking process: the collagen sponge permeated into the rings of knitted mesh. (d) BMSCs were seeded on the scaffold and cocultured for 72 h for further use. (e) BMSCs exhibited vigorous proliferation on the scaffold. (f) BMSCs retained good cellular morphology on the scaffold observed by SEM.</div>

Stem Cells International

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Figure 2: Bone Mesenchymal Stem Cells Contribute to Ligament Regeneration and Graft–Bone Healing after Anterior Cruciate Ligament Reconstruction with Silk–Collagen Scaffold 

Figure 2 | Bone Mesenchymal Stem Cells Contribute to Ligament Regeneration and Graft–Bone Healing after Anterior Cruciate Ligament Reconstruction with Silk–Collagen Scaffold 