Bone Mesenchymal Stem Cells Contribute to Ligament Regeneration and Graft–Bone Healing after Anterior Cruciate Ligament Reconstruction with Silk–Collagen Scaffold

Figure 7

HE staining of the graft–bone interface for histological observation. At 4 weeks after the reconstruction surgery, no obvious bone integration was noticed in the two groups; although, more cells were distributed in the core part in the S/C group (b) than in the S group (a). At week 16, mature trabecular bone and considerable cell invasion in the scaffold could be noticed at the graft–bone interface in the S group (c). In the S/C group, integration of the trabecular bone into the graft was observed (d). g: graft; b: bone; if: interface.