Stem Cells International / 2021 / Article / Fig 3

Research Article

Characterization and miRNA Profiling of Extracellular Vesicles from Human Osteoarthritic Subchondral Bone Multipotential Stromal Cells (MSCs)

Figure 3

Gene expression of characteristic cartilage catabolic and anabolic genes measured in (a) untreated chondrocytes (no EVs) cultured for 2, 7, and 21 days. Horizontal bars show medians, and whiskers represent interquartile range. (b) SOX9 expression in untreated and H-EV or OA-EV treated chondrocytes after 2 and 7 days. Symbols represent individual donor-derived chondrocyte cultures. (c) Chondrogenic gene expression in untreated (no EVs) and treated (H-EVs and OA-EVs) chondrocytes after 2, 7, and 21 days.

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