Hyperosmotic Stress Induces a Specific Pattern for Stress Granule Formation in Human-Induced Pluripotent Stem Cells

Figure 5

IPA network in hiPSCs/IMR90-1 and SH-SY5Y cells. (a) The top scoring IPA protein network for hiPSCs/IMR90-1 is “cell-to-cell signaling and interaction, cellular assembly and organization” and (b) in SH-SY5Y is “cellular assembly and organization, cell-to-cell signaling and interaction, reproductive system development and function,” both are depicted under the 400 mM NaCl treatment condition. The shapes represent the molecular classes of the proteins. Red represents upregulation, green represents downregulation, and color intensity represents the relative magnitude of change in protein expression. Interactions are indicated by solid lines. The protein interaction networks were generated through the use of IPA software.

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