PTHG2 Reduces Bone Loss in Ovariectomized Mice by Directing Bone Marrow Mesenchymal Stem Cell Fate

Figure 2

Intermittent injection of PTHG2 alleviated bone loss in mice induced by OVX. (a) Representative micro-CT images of femora of control group and curative groups; scale bar, 1 mm; (b) quantitative micro-CT of bone volume per tissue volume (BV/TV), number of trabeculae (Tb. N), relative bone volume fraction (BS/TV), bone surface area/bone volume (BS/BV), trabecular thickness (Tb. Th), and bone surface area/tissue volume (BS/TV); (c) H&E staining of femora. Scale bar, 100 μm; (d) quantitative number of lining cells. (e) Quantitative H&E staining of bone volume per tissue volume (BS/TV). Scale bar, 30 μm, per group (, , , ).

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