PTHG2 Reduces Bone Loss in Ovariectomized Mice by Directing Bone Marrow Mesenchymal Stem Cell Fate

Figure 3

PTHG2 protects the reduced osteoblast activity induced by OVX and weakens the formation of bone marrow adipocytes. (a) Representative images for immunofluorescence assay of osteocalcin (OCN). (b) Quantitative positive cells of OCN. (c) The relative expression of osteoblast marker gene (OCN) following PTHG2 treatment was quantified by real-time PCR. (d) Quantitative lipid droplets of H&E staining. (e) Representative images for immunohistochemistry assay of Fabp4 and (f) quantity. (g) The relative expression of adipocyte marker gene (Fabp4) following PTHG2 treatment was quantified by real-time PCR. Values presented as the (); scale bar, 50 μm; , , , .

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