3D Electrospun Nanofiber-Based Scaffolds: From Preparations and Properties to Tissue Regeneration Applications

Figure 7

Nanofiber yarn/hydrogel composite 3D scaffolds for myoblast alignment and differentiation. (a) Preparation illustration of yarn/hydrogel composite 3D scaffolds with native skeletal muscle mimicking core-shell structure (aligned nanofiber yarns by electrospinning and PEG-based hydrogel shell via photocrosslinking). (b) Highly organized C2C12 myotubes within the 3D hydrogel. (c) H&E staining images of the construct with C2C12 cell encapsulation after cultivation for seven days. Reproduced with permission from [133]. Copyright © 2015, American Chemical Society.

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