Inhibition of Notch Signaling Promotes the Differentiation of Epicardial Progenitor Cells into Adipocytes

<div>DAPT treatment reduced the differentiation of EPCs into smooth muscle cells. (a, b) Jagged-1 treatment increased the expression of smooth muscle cell specific marker <i>α</i>-SMA and Myh11, while DAPT reduced their expression. (c) Jagged-1 and DAPT treatment did not affect the expression of fibroblast specific marker periostin.</div>

Stem Cells International

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Figure 7

Figure 7: Inhibition of Notch Signaling Promotes the Differentiation of Epicardial Progenitor Cells into Adipocytes 