Research Article

Pluripotency of Dental Pulp Cells and Periodontal Ligament Cells Was Enhanced through Cell-Cell Communication via STAT3/Oct-4/Sox2 Signaling

Table 3

The cell cycle and apoptosis of PDCs and PDLCs with direct coculture at 3 d (; ).

DayG0/G1

DPCs-direct coculture
DPCs-control
PDLCs-direct coculture
PDLCs-control

Significant upregulation was observed in the percentage of direct cocultured DPCs and PDLCs in the G0/G1 phase at day 3 of direct coculture, with a corresponding decrease of cell apoptosis ( and ). PI: propidium iodinate (percentage of cells in phases); apoptosis: FITC+/PI- (early apoptotic) or FITC+/PI+ (late apoptotic).