Pluripotency of Dental Pulp Cells and Periodontal Ligament Cells Was Enhanced through Cell-Cell Communication via STAT3/Oct-4/Sox2 Signaling

Table 4

List of genes with altered expression with DPCs with indirect coculture.

Gene name	Gene symbol	Fold difference (PDLCs/DPCs vs. DPCs)	value	Functional gene grouping
Zinc finger protein, multitype 2	ZFPM2	13.77	0.0401	Embryonic development; Organ morphogenesis
Signal transducer and activator of transcription 3 (acute-phase response factor)	STAT3	8.64	0.0129	Induced pluripotent and embryonic stem cell; Organ morphogenesis; Neurogenesis
SRY- (sex determining region Y-) box 2	SOX2	3.65	0.0180	Somatic stem cell maintenance; Induced pluripotent and embryonic stem cell; Embryonic development; Organ morphogenesis; Neurogenesis; Osteogenesis
Octamer-binding transcription factor 4	OCT-4	3.53	0.0020	Somatic stem cell maintenance; Induced pluripotent and embryonic stem cell
Early growth response 3	EGR3	-8.84	0.0164	Oncogenesis
Paired box 5	PAX5	-7.42	0.0137	Organ morphogenesis
Proliferating cell nuclear antigen	PCNA	-6.66	0.0452	Cell cycle; DNA replication
Signal transducer and activator of transcription 1, 91 kDa	STAT1	-6.05	<0.0001	Hematopoiesis; Proliferation
Runt-related transcription factor 1	RUNX1	-5.16	0.0158	Organ morphogenesis; Angiogenesis; Hematopoiesis
Fibroblast growth factor 1	FGF 1	-4.01	0.0459	Cell cycle regulator; Cytokines and growth factor; Endoderm and mesoderm formation and differentiation; Organ morphogenesis
Notch 2	NOTCH2	-3.26	0.0097	Segmentation/axis/symmetry; Embryonic development; Organ morphogenesis