Stem Cells International / 2021 / Article / Tab 1

Review Article

Clinical Efficacy and Safety of Human Mesenchymal Stem Cell Therapy for Degenerative Disc Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Table 1

Characteristics of each study.

StudyRegistered numberDesignParticipantsInterventionDosageFollow-upOutcomes
MSC groupControl group

Amirdelfan et al. [18] 2021NCT01290367RCT80MSC+HAHA, 36 mVAS,ODI, AE, CSC, MIC
Noriega et al. [17] 2021NCT01860417RCT24MSCMepivacaine42 mVAS, ODI, AE
Noriega et al. [15] 2017NCT01860417RCT24MSCMepivacaine12 mVAS, ODI, AE

Note: AE: adverse event; CSC: clinically significant change; HA: hyaluronic acid; ODI: Oswestry Disability Index; MIC: minimally important change; MSC: mesenchymal stem cell; RCT: randomized controlled trial; VAS: visual analog scale.

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