Proliferin-1 Ameliorates Cardiotoxin-Related Skeletal Muscle Repair in Mice

<div>Expressions of PLF-1 in the gastrocnemius muscles at the indicated timepoints after cardiotoxin (CTX) injection. (a) Photos of a gastrocnemius mass and representative microscopy images of H&amp;E staining of the noninjured and injured muscles of mice on days 3 and 14 postinjury. Grip strength was calculated in both groups. (b) The changes of workload in the vertical direction were evaluated in both experimental groups as described in Materials and Methods. (c) Quantitative real-time PCR data show the levels of PLF-1 on days 0, 1, 3, 7, and 14 postinjury. (d) Real-time PCR data showed the PLF-1 gene expression in C2C12 myoblasts, fibroblasts, and endothelial cells inducted by CTX at 10 <i>μ</i>M. 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Stem Cells International

fig1

Figure 1

Figure 1: Proliferin-1 Ameliorates Cardiotoxin-Related Skeletal Muscle Repair in Mice 