Proliferin-1 Ameliorates Cardiotoxin-Related Skeletal Muscle Repair in Mice

<div>Recombinant proliferin-1 (rPLF-1) ameliorated skeletal muscle dysfunction and remodeling on day 14 after cardiotoxin (CTX) injection. (a) Grip strength was calculated in both groups. (b) The changes of workload in the vertical direction were evaluated in both experimental groups as described in Materials and Methods. (c-e) Quantitative data showing the cross-sectional area of the myofiber size and interstitial fibrosis (<span class="nowrap"><svg height="15.0208pt" id="M24" style="vertical-align:-3.429399pt" version="1.1" viewbox="-0.0498162 -11.5914 62.3575 15.0208" width="62.3575pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M244 635C114 635 38 519 38 422C38 317 111 240 217 240C236 240 255 244 277 256L345 292C311 140 203 39 59 15L64 -15C89 -15 150 -5 204 17C339 72 440 202 440 386C440 521 368 635 244 635ZM228 602C326 602 352 479 352 390C352 370 351 347 348 324C327 308 293 296 258 296C174 296 124 369 124 458C124 517 152 602 228 602Z"></path></g><g transform="matrix(.013,0,0,-0.013,9.147,0)"><path d="M528 54L331 254L528 455L492 493L294 291L96 493L60 455L257 254L60 54L96 16L294 217L492 16L528 54Z"></path></g><g transform="matrix(.013,0,0,-0.013,19.683,0)"><path d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 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Stem Cells International

fig2

Figure 2

Figure 2: Proliferin-1 Ameliorates Cardiotoxin-Related Skeletal Muscle Repair in Mice 