Research Article
Proliferin-1 Ameliorates Cardiotoxin-Related Skeletal Muscle Repair in Mice
Figure 5
rPLF-1 stimulated bone marrow (BM) MuSC production and mobilization in response to CTX injury. (a, b) Representative dot plots and quantitative data for the numbers of CD34+/integrin-α7+ MuSCs in BM and peripheral blood (PB). (c) After the isolation of BM-derived integrin-α7+ stem cells with magnetic beads, the cells were cultured on cover glasses for 24 hr and then subjected to double immunofluorescence with goat pAb against integrin-α7 (red) and mouse mAb against Ki67 (green). Representative double fluorescence images and quantitative data show the numbers of proliferating cells (×200 magnification). Results are (–8). vs. corresponding control groups by Student’s -test.
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