Advance of Mesenchymal Stem Cells in Chronic End-Stage Liver Disease Control

Figure 1

Main resources and underlying therapeutic mechanisms of MSCs in treating liver fibrosis/cirrhosis. MSCs are commonly obtained from bone marrow, umbilical cord blood, adipose tissue, and iPSC. MSCs exert therapeutic effects through paracrine, immunomodulation, hepatocyte-like cell differentiation, oxidative stress regulation, cell ferroptosis regulation, cell autophagy regulation, and MSCs-mitochondrial transfer.