Human Brain Organoid: A Versatile Tool for Modeling Neurodegeneration Diseases and for Drug Screening

Figure 3

The cryo-preserved human colon organoids with APC^-/-; KRAS^G12D mutation could confer the long storage and re-grown upon cryo-recovery for expansion to make the culture operation alike for the cell lines. This strategy could significantly overcome the bottleneck limitation of the organoid supply for the ultra-high-throughput screening (UHTS) in 384-well and 1538-well plates.